Great River Road - Missouri
Places to Visit

• Fort Defiance State Park (IL)

  The park commemorates the Civil War Fort Defiance, commanded by General U.S. Grant. The site offers a breathtaking view of the river.

  Distance from byway:	On the byway
  Directions:	Located about 2 miles south of Cairo, Illinois, at the extreme southern tip of Illinois.

• Canton-Lagrange (MO)

  These riverside towns offer places to play along the river.

  Distance from byway:	On the byway
  Directions:	Off of US Highway 61 in Missouri.

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  Clarksville (MO)

  Clarksville is a quaint small town along the byway.

  Distance from byway:	On the byway
  Directions:	Off of State Road 79

• Hannibal (MO)

  This quaint river town was home to Mark Twain.

  Distance from byway:	On the byway
  Directions:	Off of US 24/61 in Missouri

• Imperial (MO)

  This town is just a stone's throw away from two State Historic Sites.

  Distance from byway:	On the byway
  Directions:	Off of US 61 in Missouri.

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  Louisiana (MO)

  The city of Louisiana offers the traveler food and lodging along the Byway.

  Distance from byway:	On the byway
  Directions:	Off of State Road 79 on the Great River Road in Missouri.

• Mark Twain Cave (MO)

  Located in Hannibal, this cave was the setting for some of Tom Saywer's adventures.

  Distance from byway:	On the byway
  Directions:	Hannibal, Missouri

• Mark Twain State Park (MO)

  Explore Mark Twain's birthplaces and take a boat ride on Mark Twain Lake.

  Distance from byway:	On the byway
  Directions:	45 minutes west of Hannibal

• New Madrid (MO)

  An earthquake disrupted life in New Madrid in 1811.

  Distance from byway:	On the byway
  Directions:	Off of State Highway 79 in Missouri.

• Ste. Genevieve (MO)

  Ste. Genevieve is the oldest European settlement in Missouri.

  Distance from byway:	On the byway
  Directions:	Off of US Highway 61 in Missouri