Ohio River Scenic Byway
Getting to the Byway

Nearby Cities

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Champaign, IL (211 miles / 337.6 km, 3 hours 30 minutes)
Start: City Marker I-57 southbound, Champaign, IL
N 40.120° W 88.306° [?]
Directions:
  • Take I-57 south.
  • Continue onto I-64 east, just south of Mt. Vernon, IL.
  • Take exit 110 for US-45 and head south.
  • Turn east off US-45 onto IL-141.
  • Follow IL-141 east to New Haven to enter the byway.
Junction with byway: End Marker Intersection of IL-141 and CR-8 (1200 E), New Haven IL
N 37.908° W 88.154° [?]
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Charleston, WV (54 miles / 86.4 km, 53 minutes)
Start: City Marker I-64 westbound, Charleston, WV
N 38.358° W 81.644° [?]
Directions:
  • Take I-64 West to Huntington, WV and cross the Ohio River at any Ohio River bridge to enter the byway.
Junction with byway: End Marker OH-7, OH
N 38.422° W 82.493° [?]
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Cincinnati, OH (On the byway)
Start: City Marker Cincinnati, OH [6]
N 39.094° W 84.518° [?]
Directions:
  • The byway runs along the river adjacent to US-50.
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Cleveland, OH (163 miles / 260.8 km, 2 hours 40 minutes)
Start: City Marker I-77 southbound, Cleveland, OH
N 41.488° W 81.665° [?]
Directions:
  • Take I-77 south to Marietta, OH where you enter the byway.
Junction with byway: End Marker OH-7 from I-77, Marietta, OH
N 39.410° W 81.427° [?]
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Columbus, OH (88 miles / 140.8 km, 2 hours)
Start: City Marker US-23 southbound, Columbus, OH
N 39.962° W 83.001° [?]
Directions:
  • Take US-23 south to US-52 in Portsmouth where you enter the byway.
Junction with byway: End Marker Intersection of US-23 and US-52, Portsmouth, OH
N 38.739° W 82.996° [?]
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Indianapolis, IN (109 miles / 174.4 km, 1 hour 40 minutes)
Start: City Marker I-65 southbound, Indianapolis, IN
N 39.749° W 86.143° [?]
Directions:
  • Take I-65 south to the Jeffersonville exit, mile marker 0.
  • Follow the exit ramp to Market Street and turn right.
  • Turn left at the next stop sign onto Southern Indiana Ave. and right onto Riverside Dr. where the byway runs east and west along the river.
Junction with byway: End Marker Entrance to US-31 from Old IN-62, Jeffersonville, IN
N 38.279° W 85.750° [?]
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Memphis, TN (164 miles / 262.4 km, 2 hours 30 minutes)
Start: City Marker I-55 southbound, Memphis, TN
N 35.126° W 90.067° [?]
Directions:
  • Take I-55 north to Sikeston, MO.
  • Merge north onto I-57, cross over the Mississippi River into Illinois, and take Exit 1.
  • Take IL-3 east to US-51 where you enter the byway.
Junction with byway: End Marker Intersection of IL-3 and US-51, Cairo IL
N 37.038° W 89.188° [?]
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Nashville, TN (170 miles / 272.0 km, 2 hours 50 minutes)
Start: City Marker I-24 northbound, Nashville, TN
N 36.177° W 86.772° [?]
Directions:
  • Take I-24 northwest to Paducah, KY.
  • Get on US-60 and go west to Cairo, IL.
  • Travel northwest on US-51 where the byway begins.
Junction with byway: End Marker US-51, Cairo, IL
N 36.996° W 89.162° [?]
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Pittsburgh, PA (52 miles / 83.2 km, 54 minutes)
Start: City Marker I-79 southbound, Pittsburgh, PA
N 40.416° W 80.104° [?]
Directions:
  • Take I-79 south to 1-70 in Washington, PA to Bridgeport, OH where you enter the byway.
Junction with byway: End Marker OH-7, Bridgeport, OH
N 40.072° W 80.740° [?]
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St. Louis, MO (143 miles / 228.8 km, 2 hours 30 minutes)
Start: City Marker I-64 eastbound, St. Louis, MO
N 38.629° W 90.159° [?]
Directions:
  • Take I-64 east to Exit 110, Route 45.
  • Travel south on Route 45 to Route 141.
  • Follow Route 141 east to enter the byway.
Junction with byway: End Marker Intersection of IL-141 and CR-8 (1200 E), New Haven IL
N 37.908° W 88.154° [?]
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Terre Haute, IN (109 miles / 174.4 km, 2 hours 20 minutes)
Start: City Marker US-41 southbound, Terra Haute, IN
N 39.465° W 87.414° [?]
Directions:
  • Take US-41 south through Evansville.
  • Exit on Veteran’s Memorial Parkway.
  • Follow the parkway for 3.1 miles before connecting to Riverside Dr. in Evansville.
Junction with byway: End Marker IN-66, Evansville, KY
N 37.977° W 87.550° [?]